Japanese scientists have achieved a new breakthrough that could make a fundamental change in the treatment of obesity and diabetes, which have a significant impact on human health. Researchers from Osaka University have proposed a single-use genetic intervention technology, which is different from conventional weight loss drugs and regular injections, reported news-medical.net.
In this method, scientists departed from traditional gene therapy: instead of eliminating the root of the problem—harmful mutations—they focused on introducing a special gene into the body. This gene provides the production of exenatide, which replaces the GLP-1 hormone in the body. On the other hand, exenatide is used in the composition of medicines, but it requires regular intake and constant injections.
According to the head of the research, Keiichiro Suzuki, the new approach, combining the possibilities of gene therapy and biological drugs, adapts the body for long-term and continuous production of the necessary substance.
"Our approach has combined the advantages of gene therapy and biological drugs. Our study showed that by introducing the necessary gene into the body, the cells themselves can continue to produce the required substance for several months—this eliminates the need for regular injections," said Keiichiro Suzuki, the head of the research.
In the experiments conducted, the exenatide level in the blood of mice with the introduced gene remained stable and uninterrupted for several months. As a result, the mice ate less, their weight gain slowed down, and the level of glucose in their blood was better controlled.
It is noted with optimism and hope that no negative or adverse effects were observed. According to the scientists, this method may be useful not only for treating obesity but also for type 2 diabetes and other chronic diseases not related to specific genetic mutations. Such an innovative therapy achievement may become a reason to reconsider traditional medical concepts.
If the new research results are confirmed, a single-use genetic treatment method will free patients from lifelong injections and significantly improve their quality of life. In the future, based on this technology, a new generation of drugs with long-lasting effects and capable of replacing regular injections may appear.
It should be noted that the development of such technologies may play an important role in stopping the diabetes and obesity epidemic in the future. This scientific revolution initiated by Japanese scientists promises a new direction for medicine worldwide. Read 'Zamin' on Telegram!
Ctrl
Enter
Did you find a Mistake?
Highlight the phrase and press Ctrl+Enter Related News
