Scientists have proposed an unconventional vaccine delivery method using regular dental floss, which they believe could trigger a strong immune response both locally and systemically. According to their research, delivering vaccines through the natural channel between the teeth and gums—the gingival duct—could be more effective than traditional methods.
The technique was tested on mice, and the results showed that dental floss treated with nanoparticles containing flu virus proteins activated lymph node activity. Unlike traditional sublingual methods, this technique showed a stronger and longer-lasting immune response, comparable to nasal vaccinations.
Moreover, the new method proved effective regardless of age, food, or water consumption, making it convenient and injection-free. The researchers also tested this method in humans using fluorescent dyes, confirming that substances applied to dental floss indeed reached the gingival space.
This method not only simplifies the vaccination process but also opens up new possibilities for disease prevention with minimal discomfort and cost. Scientists are now planning to continue trials and expand the testing of this method, which could lead to significant improvements in vaccination processes and offer new solutions for disease prevention.
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